Fenben Lab - Fenbendazole Powder
Pharmacology and Mechanism of Action Benzimidazole antiparasitic drug. Like other benzimidazoles, fenbendazole produces a degeneration of the parasite microtubule and irreversibly blocks glucose uptake in parasites. Inhibition of glucose uptake causes depletion of energy stores in the parasite, eventually resulting in death. However, there is no effect on glucose metabolism in mammals. Indications and Clinical Uses Fenbendazole is effective for treatment of numerous helminth intestinal parasites including Toxacara, Toxascaris, Ancylostoma, and Trichuris. it is effective for most intestinal helminth parasites and also against nematodes. it also has been used for pulmonary helminths (lungworms), but longer duration of treatment is needed. Fenbendazole has been effective for treatment of Giardia, but higher doses are needed and there may be failure rates as high as 50%. It is effective in cats for treatment of lungworms, flukes, and a variety of helminth parasites. Fenbendazole fen-b...